Autonomic nervous system involvement in pulmonary arterial hypertension
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چکیده
منابع مشابه
Autonomic nervous system involvement in pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is a chronic pulmonary vascular disease characterized by increased pulmonary vascular resistance (PVR) leading to right ventricular (RV) failure. Autonomic nervous system involvement in the pathogenesis of PAH has been demonstrated several years ago, however the extent of this involvement is not fully understood. PAH is associated with increased sympathetic...
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P ulmonary arterial hypertension (PAH) is a rare dyspnoea-fatigue syndrome defined by an isolated increase in pulmonary vascular resistance (PVR) and eventual right ventricular failure [1]. In spite of progress achieved during the last two decades, the condition remains severe, with a median survival limited to 5–6 yrs and persistent functional limitation in approximately half of the survivors ...
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That hypertension is due to a derangement of sympathetic and parasympathetic cardiovascular regulation is one of the most widely accredited and tested hypotheses in cardiovascular research. Its proposal followed from the demonstration that autonomic cardiovascular influences play a fundamental role in homeostatic control of the cardiovascular system. In animal models of hypertension, both an in...
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ژورنال
عنوان ژورنال: Respiratory Research
سال: 2017
ISSN: 1465-993X
DOI: 10.1186/s12931-017-0679-6